It has been reported that both upper airway narrowing and increased airway resistance may contribute to the underlying pathogenesis of OSA, leading to symptoms of loud snoring, apnea, and systemic complications if not properly treated. Within this tube, reduced airflow from the nasal cavity and narrowing of the upper airway increases negative pressure in the pharyngeal airway and predisposes the pharynx to collapse. In the Starling resistor model, the upper airway is described as a hollow tube. Obstructive sleep apnea (OSA) is a common sleep disorder characterized by upper airway collapse, causing reduction or cessation of airflow during sleep. Therefore, resolution of these issues is needed to enhance CPAP compliance for control of OSA. Subjective discomfort including inconvenience, mouth dryness, and chest discomfort were the main problems for OSA subjects who did not comply with CPAP therapy.Įxcessive upper airway blockage in the nasal cavity and oropharynx was predominant in CPAP nonadherent subjects, which might cause the reported subjective discomfort that reduces CPAP compliance. In addition, CPAP nonadherent subjects showed considerably bigger tonsils and higher grade palatal position comparing with the CPAP adherent subjects. Higher grades of septal deviation and hypertrophic change of the inferior turbinate were observed more in the CPAP nonadherent group.

Mean body mass index of CPAP nonadherent group was significantly higher than CPAP adherent group. There were no statistically significant differences in sleep parameters between CPAP-adherent patients and CPAP nonadherent subjects. The medical records were reviewed for demographic and polysomnographic data and anatomic findings of the nasal cavity and oropharynx.Ģ4 patients who adhered to CPAP therapy and 23 patients who were nonadherent were enrolled in the study. The medical records of 47 OSA subjects who received CPAP therapy as a first-line treatment modality were retrospectively reviewed. This study aims to analyze the anatomic and clinical factors of OSA subjects who failed to comply with CPAP therapy. Although continuous positive airway pressure (CPAP) is the most effective treatment modality, poor adherence still remains a problem for obstructive sleep apnea (OSA) treatment and there is little evidence regarding how this might be improved.

Upper chest discomfort abd cpap